The Anabolic Roundtable Ep.7 — Anabolic Peptide Tier List

Lowest-tier source — bodybuilding PED roundtable, NOT medical/educational

This is an enhanced-bodybuilding podcast ranking compounds for muscle gain. It is not clinical or peer-reviewed; treat everything as [anecdote-bb] (bodybuilding-community opinion) — the weakest evidence class in this base, below the physician transcripts and far below kb-paper nodes. Deliberately excluded (out of policy + hazardous): the source’s performance-dosing of insulin (25–50 IU in non-diabetics), EPO (hematocrit 54–60), anabolic steroids / TRT+ / the “trinity stack,” mega-dose melatonin (30 mg), and supraphysiologic GH bodybuilding ramps. These conflict with this base’s research-use-only / no-human-dosing-as-advice policy (see Strategy §9) and carry serious harm risk. They are not captured here and must not be threaded into any note as protocol. Research/educational use only. Source: YouTube — e9OAzmNJFaM (No verbatim transcript stored for this source, by design — only the in-policy peptide knowledge below.)

In-policy peptide knowledge captured

• BPC-157 + TB-500 — rated the two peptides that “actually do something” (A-tier for healing). Reiterates BPC-157’s main mechanism as GH-receptor upregulation (pair with GH for tendon repair) and bidirectional angiogenesis (can downregulate blood flow regionally → speculative anti-cancer nuance). A coach reports ~15 months oral BPC-157 (400–800 mcg) alongside KPV resolving gut/gluten-exposure symptoms (clean GI panel). TB-500’s ~5 human-relevant studies reportedly show healing ≈ full-length thymosin β4 (so compounders often use β4 itself). [~01:20–01:27]
• GHK-Cu — used for localized collagen / ‘site enhancement’ by injection (e.g. building a triceps sweep) — effective but very painful, needing deep-tissue massage to break up collagen filaments; topical useful for skin and even dissolving calluses. Panel felt GH outperformed it for this. [~01:13–01:19]
• Epithalon — community anti-aging dosing: “Ukrainian” ~50 mg / “Russian” ~100 mg every ~6 months (telomerase/anti-aging; effect unverifiable for ~10–20 yrs). Notes astragaloside IV (from astragalus) as a cheaper telomerase-activation alternative. [~01:30–01:36]
• IGF-1 LR3 — rated F-tier: hit-or-miss, brand/batch-dependent, and on blood work does not meaningfully raise serum IGF-1 (vs recombinant IGF-1/Increlex, which does); many gray-market vials labelled “1 mg” may be ~100 mcg. [~00:44–00:50]
• MOTS-C — A-tier for performance; the SLU-PP-332 + methylene blue + MOTS-c mitochondrial stack reported to improve energy, training capacity, and resistance to off-season fat gain. [~01:42–01:48]
• SS-31 — 5 mg ×5 days/wk × ~3 weeks gave no obvious subjective benefit atop the rest of the mito stack; best-claimed use is pre-surgery (raising mitochondrial function/density before extensive procedures). [~01:49–01:53]
• Ipamorelin (secretagogue quant.) — estimate: ~125 mcg ipamorelin → only ~0.5–0.7 IU GH released; saturation ~125–150 mcg; favored over GHRP-2/6 for lacking prolactin/cortisol effects; cost-per-IU makes secretagogues poor value vs pharma GH for muscle. [~00:22–00:26]
• HGH — in these circles rated just below testosterone (“triforce of anabolism” = test + GH + insulin); SubQ absorption ~4 h, single nightly dose standard. (Supraphysiologic bodybuilding dosing in the source is intentionally not captured.) [~00:06–00:15]

New compounds discussed without a note yet (candidates)

• FOXO4-DRI — a senolytic peptide (a FOXO4 antagonist/decoy) that pushes senescent (‘zombie’) cells to apoptosis; pairs conceptually with Epithalon on the anti-aging axis. Genuinely interesting candidate.
• Increlex (recombinant IGF-1 / “incx”) — prescription IGF-1 (pediatric growth failure); the only IGF-1 form the panel says reliably raises serum IGF-1; ranked highly. Candidate (Rx, not catalog).
• MGF (mechanical growth factor) — panel consensus: ineffective (“junky”); useful as a debunking note.
• Follistatin / ACE-031 / ACE-083 — myostatin inhibitors; “great on paper,” no real-world results, unaffordable; skeptical note.
• Astragaloside IV — telomerase-activation alternative to epitalon.

Excluded content (recorded for transparency, NOT captured as knowledge)

Insulin performance dosing; EPO/hematocrit protocols; anabolic-steroid cycle design; mega-dose melatonin; supraphysiologic GH ramps; generic/underground-GH sourcing. Out of policy and hazardous — see the safety banner.