[anecdote] Liver-derived IGF-1 is released in response to GH; anabolic and regulates blood-sugar metabolism, synergistic with GH. — Huberman 00:43–00:44
[anecdote] IGF-1 output varies by dog breed: high IGF-1 (Great Dane) tracks shorter lifespan vs low IGF-1 (Chihuahua) — the growth-vs-longevity trade-off. — Bakri 02:08
[anecdote-bb] Rated F-tier: hit-or-miss, brand/batch-dependent, and does not meaningfully raise serum IGF-1 on blood work (vs recombinant IGF-1/Increlex, which does); many gray-market ‘1 mg’ vials may be ~100 mcg. — Anabolic Roundtable ~00:44–00:50