History of growth hormone-releasing peptides

Key finding

First-hand historical account of the discovery of growth-hormone-releasing peptides (GHRPs) and the path to ghrelin — establishing the GHS-receptor/ghrelin axis that GHRPs act on.

Method / model

Historical review by the GHRP discoverer.

Relevance

Origin reference for the GHRP class (GHRP-6, GHRP-2, Hexarelin, Ipamorelin).

Bowers, C.Y. (2012). History of growth hormone-releasing peptides. Endocrine, 14(1), 137-147.