What it is
Peptides acting on it
Evidence
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[educational]TB4’s core mechanism: its aa 17–23 segment (= the TB500 fragment) binds G-actin, stabilising actin building blocks for cell migration and angiogenesis (endothelial cells lining new vessels) — the basis of its tissue-repair effect. — TB500 deep dive -
[literature]The actin-binding 17–23 fragment itself is now in a registered Phase 1/2 human trial (TB-500 vs placebo, stable ASCVD, 2026, no results yet). — SOURCE-tb500-ascvd-rct-nct07487363