Definition

Why it matters

  • [anecdote-bb] Secretagogues (GHRH-analogs + GHRPs) coax the pituitary to release its own GH, so output is capped by pituitary capacity and blunted by somatostatin/IGF-1 feedback. Bodybuilding consensus across sources: useful but modest vs exogenous GH, which raises serum GH/IGF-1 far more per dollar — especially past ~age 40. — Vigorous Steve