Thymulin

Overview

  • [educational] The 9-amino-acid, zinc-dependent thymic peptide (the French-isolated “true” main thymus hormone) — the marker of thymus function, falling with age. Distinct from the Russian polypeptide mix “thymalin”. — Bakri

Mechanisms

  • [educational] Develops NK/T-cells and, in animal data, sensitises end-organs to their target hormone — e.g. HCG + thymulin yields more testosterone than hCG alone (a thymus↔reproduction link). — Bakri

Evidence

  • [educational] Has a very short half-life → the practical goal is raising endogenous thymulin, which requires adequate zinc (falling thymulin is the earliest sign of zinc depletion, before serum/RBC zinc). — Bakri

Anecdotes

Physician protocols

Practical notes